Milestones from our joint work with KIQBNS.
At the 29th Annual Meeting of the Korean Society for Brain and Neural Sciences (Daejeon Convention Center), KIQBNS and Q-Gen Bio jointly presented findings (poster P-679) that wake-state K-complex-like responses coincide with cerebral blood flow and heart-rate variability in the roughly 0.1 Hz Mayer-wave band. This remains an early feasibility study in a small number of subjects; the team named the framework the ‘WI-KC-delta-Mayer-wave framework.’
A follow-on international patent application (PCT/KR2026/012515, priority date August 26, 2025) covering a closed-loop safety design based on bio-impedance feedback was filed on August 26, 2026, along with a corresponding domestic application with KIPO; a search opinion from the International Searching Authority is expected in the second half of 2026.
Q-Gen Bio Ltd. was formally incorporated in Seoul on August 4, 2026, as KIQBNS's commercialization spin-off.
Selected as a resident company of the Seoul Bio Hub anchor facility, establishing a base at the Seoul Bio-Innovation Community Center in Jongam-dong.
At the 7th AKN (Association of Korean Neuroscientists in America) Symposium, the team presented tRFPM-based research on clearing brain waste products and a proposed mechanism for addressing ARIA, a side effect of antibody-based dementia therapies.
An international patent application (PCT/KR2025/023282), with a priority date of December 31, 2024, received a favorable search report from the International Searching Authority, affirming novelty, inventive step, and industrial applicability across all of claims 1–9.
Building on a priority date of December 31, 2024, the team formally filed the international patent application PCT/KR2025/023282 on December 31, 2025, along with a corresponding domestic application with the Korean Intellectual Property Office (KIPO).
A provisional filing establishing the priority basis for the second international patent (PCT/KR2026/012515), covering a closed-loop safety design based on bio-impedance feedback, was made with KIPO on August 26, 2025.
At K-Brain 2025 in Songdo, founder Kim Kwang-woo presented his first poster, titled “Real-Time Induction of K-Complexes by Non-Invasive DBS,” on inducing wake-state K-complex-like activity, marking his debut in the formal scientific community.
A provisional filing establishing the priority basis for PCT/KR2026/012515 was made with KIPO on August 26, 2025.
Founder Kim Kwang-woo became a member of KSBNS, formally joining Korea's academic neuroscience community.
A provisional filing establishing the priority basis for PCT/KR2025/023282 was made with the Korean Intellectual Property Office (KIPO) on December 31, 2024, introducing the new terms ‘WI-KC (Wake-Induced K-Complex)’ and ‘WIKC-tRFPM.’
The Korea Institute of Quantum Brain & Neural Sciences (KIQBNS) was founded in January 1985, laying the research foundation that spans more than four decades.